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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
6.06
Human Site:
S369
Identified Species:
10.26
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S369
C
P
G
P
L
D
S
S
A
F
L
S
S
D
F
Chimpanzee
Pan troglodytes
XP_509441
819
90122
L329
L
S
V
P
Q
P
F
L
P
V
F
T
M
P
L
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
S369
C
P
G
P
L
D
S
S
A
F
L
N
S
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
G369
Q
A
R
N
S
C
S
G
P
L
D
P
N
P
F
Rat
Rattus norvegicus
Q6AXT8
471
49872
R31
R
D
R
R
E
R
L
R
Q
L
A
L
E
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
Q369
P
E
P
P
L
L
T
Q
P
C
P
P
Q
P
S
Frog
Xenopus laevis
NP_001084764
548
60887
L108
T
L
A
Y
S
G
K
L
V
S
P
K
W
K
N
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
H362
P
S
A
P
L
P
G
H
L
S
V
A
N
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Q364
Q
Q
Q
V
N
N
T
Q
Q
Q
Q
H
Q
S
T
Honey Bee
Apis mellifera
XP_394429
1014
115124
I487
Q
S
I
H
A
N
Q
I
S
P
I
T
N
L
V
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
Q372
S
Q
I
S
Q
P
S
Q
Q
L
Q
H
Q
I
Q
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T485
L
G
G
G
L
Q
L
T
D
L
Q
N
T
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
M583
L
S
Q
G
N
S
W
M
S
L
A
G
S
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
0
93.3
N.A.
13.3
0
N.A.
N.A.
13.3
0
13.3
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
13.3
0
100
N.A.
20
0
N.A.
N.A.
20
0
33.3
N.A.
13.3
33.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
8
0
0
0
15
0
15
8
0
0
0
% A
% Cys:
15
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
15
0
0
8
0
8
0
0
15
8
% D
% Glu:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
15
8
0
0
0
29
% F
% Gly:
0
8
22
15
0
8
8
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
15
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
8
0
0
8
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% K
% Leu:
22
8
0
0
36
8
15
15
8
36
15
8
0
8
15
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
15
15
0
0
0
0
0
15
22
0
8
% N
% Pro:
15
15
8
36
0
22
0
0
22
8
15
15
0
22
0
% P
% Gln:
22
15
15
0
15
8
8
22
22
8
22
0
22
8
8
% Q
% Arg:
8
0
15
8
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
29
0
8
15
8
29
15
15
15
0
8
22
8
8
% S
% Thr:
8
0
0
0
0
0
15
8
0
0
0
15
8
15
8
% T
% Val:
0
0
8
8
0
0
0
0
8
8
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _